Review published in Frontiers in Neuroscience: NCOA4-Mediated Ferritinophagy: A Potential Link to Neurodegeneration

Maria Quiles del Rey writes a review evaluating the potential role of NCOA4-mediated ferritin autophagy in modulating neurodegeneration. Given the link between decreased autophagy and increased iron accumulation in the aging brain and especially in patients with neurodegeneration, Maria reviews the available evidence and proposes interesting questions for future study of NCOA4.