Aditya Jain joins the lab for a summer undergraduate research fellowship! Aditya just completed high school at Westview High School in Portland, Oregon. During high school Aditya began his research career in earnest studying important aspects of lung cancer and immunotherapy. His work on small cell lung cancer with Dr. Tim Mitin at OHSU was published in the Journal of Thoracic Oncology and the Lung Cancer Journal. Aditya will begin his freshman year at Boston University this September as a Trustee Scholar. His long-term goal is to become a physician-scientist after completing a MD-PhD program. Welcome to the lab!
Work from the group of Dr. Jennifer Tseng (then at BIDMC and now the new chief of surgery at Boston Medical Center) shows that stereotactic body radiotherapy could be a promising treatment option for patients with unresected pancreatic cancer. This study was published in the journal Cancer. Dr. Mancias is glad to be part of this work and support further research into new therapies for pancreatic cancer as part of the Pancreas and Biliary Tumor Center at Dana-Farber/Brigham and Women's Cancer Center. To the left: survival curve of various treatment options for patients with unresected pancreatic cancer. Below: example stereotactic body radiation therapy treatment plan. Read more about the study here.
Vinay Eapen is awarded a post-doctoral fellowship from the Jane Coffin Childs Memorial Fund for Medical Research!
Congratulations Vinay! Vinay is awarded a post-doctoral fellowship from the Jane Coffin Childs Memorial Fund for Medical Research for his proposal that seeks to understand the role of selective autophagy in cancer. Vinay is a joint post-doctoral fellow in the Mancias Lab and the Harper Lab.
From the Jane Coffin Childs Memorial Fund for Medical Research website:
"The Jane Coffin Childs Memorial Fund for Medical Research (known colloquially as the JCC Fund) was established in 1937 for the purpose of supporting research into the causes and treatment of cancer. The Fund has taken a broad approach to the study of cell growth and development, emphasizing the study of the basic biology and chemistry of the underlying processes. The Fund has increasingly focused its resources on the funding of three-year postdoctoral Fellowships, supporting Fellows selected by its Board of Scientific Advisers from among the best young scientists at what is often a critical stage in their careers."
Amrita Singh Chandhoke, PhD joins the lab! Amrita recently completed her graduate studies at the University of Calgary in the lab of Dr. Shirin Bonni. Amrita studied TGF-beta signaling and its regulation by Smurf2. Amrita joins the lab to begin work on understanding therapeutic resistance mechanisms in pancreatic cancer.
The Hale Center, led by Dr. Brian Wolpin, is comprised of a multi-disciplinary team of DFCI investigators dedicated to pancreatic cancer research. At their monthly meeting, the Mancias Lab presents our work on 'Compensatory Metabolic Networks in Pancreatic Cancers Upon Perturbation of Glutamine Metabolism.' The Mancias Lab looks forward to future collaborations with the Hale team!